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News today announced the Salk team expanded after their previous development of a drug candidate, called J147, which takes a different tack by focusing on Alzheimer's major risk factor-old age. Inside the new work, the team demonstrated that the drug prospect worked well in a mouse model of increasing age not typically used in Alzheimer's research. When these mice were treated with J147, they had better memory and cognition, much healthier blood vessels in the brain and other better physiological features,
News today announced "Initially, the impetus was going to test this drug in a novel animal model that was more similar to 99 per cent of Alzheimer's cases, " claims Antonio Currais, the business lead author and an affiliate of Professor David Schubert's Cellular Neurobiology Laboratory at Salk. "We would not predict we'd see this kind of anti-aging effect, but J147 made old mice appear to be they were young, established on a number of physiological parameters. "
News today announced alzheimer's disease is an intensifying brain disorder, recently placed as the 3 rd leading cause of death in the United States and affecting more than five million Americans. It is also the most typical cause of dementia in older people, in line with the National Institutes of Health.
"While most drugs developed in the previous 20 years target the amyloid plaque deposits in the brain (which are a trademark of the disease), none have proven effective in the medical clinic, " states Schubert, older author of the analysis. Broadening the Fight to Additional Common DementiasSeveral years back, Schubert and his co-workers started to approach the treatment of the disease from a new perspective.
Tin m?i hôm nay cho bi?t l?c l??ng Salk ?ã m? mang ch??ng trình l?n m?nh áp d?ng ma túy tr??c ?ây c?a h?, ???c g?i là J147, v?i m?t ph??ng pháp ti?p c?n khác nhau b?ng cách th?c nh?m ch? tiêu t?i y?u t? nguy c? chính c?a b?nh Alzheimer. Trong nghiên c?u m?i này, nhóm nghiên c?u ?ã ch? ra r?ng ng??i tìm vi?c v? thu?c ?ã làm vi?c t?t trong mô ph?ng lão hóa chu?t không th??ng ???c tiêu dùng trong nghiên c?u c?a Alzheimer. khi nh?ng con chu?t này ???c ?i?u tr? b?ng J147, chúng v?i trí t??ng và nh?n th?c r? h?n, nh?ng m?ch máu kh?e m?nh h?n trong não và các tính n?ng sinh lý c?i ti?n khác <a href="http://vitaminll.blogspot.com/2017/04/mot-truong-ai-hoc-tai-nuoc-my-ua-phap.html">vitaminll.blogspot.com</a>
Tin m?i hôm nay cho hay ông Antonio Currais, tác gi? chính và là thành viên c?a Phòng th? nghi?m Sinh lý h?c Cellular c?a Giáo s? David Schubert t?i Salk, cho bi?t: "Ban ??u, ??ng l?c là th? nghi?m chi?c thu?c này trong 1 mô ph?ng ??ng v?t m?i l?, nh? v?y nh? 99% tr??ng h?p m?c b?nh Alzheimer. "Chúng tôi ko d? ?oán chúng ta s? th?y hi?u ?ng ch?ng lão hóa này, nh?ng J147 ?ã khi?n cho chu?t già trông gi?ng nh? chúng còn tr?, d?a trên m?t s? thông s? sinh lý."
Tin m?i hôm nay cho bi?t b?nh Alzheimer là b?nh r?i lo?n não ti?n b?, cách ?ây không lâu ???c x?p h?ng nh? là duyên do th? ba gây t? vong ? Hoa K? và ?nh h??ng ??n h?n n?m tri?u ng??i M?. Theo Vi?n Y t? ??t n??c, ?ây c?ng là duyên c? nhi?u nh?t c?a ch?ng sa sút trí óc ? ng??i l?n tu?i.

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